Loop Diuretics may Cause Bone Loss in Elderly Men

The study grades be published in the August 30 circulate of the New England Journal of Medicine by a subdivision co-led by a University of Michigan Cardiovascular Center surgeon and a Washington Hospital Center cardiologist.

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Led by Lionel S. Lim, M.D., M.P.H., of Griffin Hospital, Derby, Conn., the researchers examine 3,269 men age 65 and older (average age 72.7). At an foundation going over concerning 2000 and 2002 and at a continuation pop in an standard of 4.6 years subsequent, the men answered question bestow or take a few medication splurge and bring in containers in favour of all medication taken during the bygone 30 days. Bone mineral density of the complete hip and two subregions be also measured.

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"Compared with rates of hip bone loss among non-users of diuretics, adjusted rates of loss be about two-fold greater among intermittent loop diuretic users and about 2.5-fold greater among continuous loop diuretic users," the authors wrote.

The findings were related at the subregions of the hip, and they added by truism: "We conclude that loop diuretic use in older men in associated with increased rates of hip bone loss. Our findings bring forward that robustness vigilance provider should take into narrative loop diuretic use when evaluate older men for risk factors for bone loss and fracture risk." The study was published in the recent distribute of Archives of Internal Medicine, one of the JAMA/Archives monthly.

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