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"We be very captivated with the results of this far-reaching Phase 2a research and look forward to projected study which will further judge the eventual of PS433540, probably even elapsed blood pressure lower," said Joseph A. Mollica, Ph.D., Chairman of the Board and Interim President and Chief Executive Officer of Pharmacopeia. "We consider PS433540's double ridiculous parts of bustle may have a positive effect on diabetic kidney disease." Patients with diabetes are at an increased risk for several complications, with high blood pressure and diabetic kidney disease. Up to 73 percent of patients with diabetes have be or are man treated for high blood pressure,(5) and an estimated 20-30 percent of diabetic patients will progress to diabetic kidney disease,(6) a cataclysmic disease that may require patients to run through dialysis or a kidney transplant.(7) Pharmacopeia by a whisker initiate a 12-week, Phase 2b clinical trial with PS433540 to weigh wakeful to the compound's place of protection and efficacy at three not resembling dose versus placebo in 375 subject with Stage I and Stage II hypertension. The study will also relate blood pressure reductions for all dose with irbesartan. Pharmacopeia anticipates achievement of the Phase 2b trial at the shutting of 2008.
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